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This activity is intended for healthcare professionals practicing in
managed care environments.
This activity is supported by
an educational grant from
Psoriasis is a complex, chronic, immune-mediated inflammatory
disease that affects approximately 7 million of the population in
the United States. Psoriasis is a periodic flare-up of sharply
defined red patches, covered by a silvery, flaky surface. The main
disease activity leading to psoriasis occurs in the epidermis, the
top five layers of the skin. The disease most commonly appears on
the skin of the scalp, elbow, knees, and lumboscaral areas of the
body. Many of the patients are not receiving the appropriate
treatment discussed in the current guidelines and standards of care.
Psoriasis is a complex disease to manage, but the goal should be a
patient-centered treatment that reduces disease burden, improves on
quality-of-life, and addresses the risks of systemic complications
and comorbid conditions. The under diagnosis and treatment of
psoriasis continues to be a serious concern
Once psoriasis is diagnosed through a physical examination and a
skin biopsy, treatment of the disease will depend on which type of
psoriasis, where it is, and the severity of it. Newer biologics are
more targeted to the inflammatory pathways involved in psoriasis,
which works by blocking two proteins -- interleukin-17 and -23.
These newer agents have been shown to be effective in treating
psoriasis and could also be safer given their more specific action
on the immune system. Treatments that inhibit IL-23 and IL-17 have
shown promising data in safety and efficacy in clinical trials of
moderate-to-severe psoriasis. Recent breakthroughs, and a better
understanding of the pathogenesis of psoriasis, have been translated
into targeted and highly effective therapies.These new options have
shown improved efficacy and safety in psoriasis, and healthcare
professionals must be educated on these agents and the potential
risks that come along with any treatment option.
Upon completion of this
activity, participants will be able to:
Analyze the etiology,
pathophysiology, and diagnostic considerations of psoriasis
Develop a management plan, using the
most recent guidelines, for newly diagnosed patients with
psoriasis based on disease severity
Examine the safety and effectiveness
of novel targeted treatments for psoriasis patients that have an
inadequate response to conventional therapies
Develop new strategies to overcome
different challenges of psoriasis, including adverse effects of
novel therapies, patient adherence and managing comorbidities
Explore the role of a
multidisciplinary care team, using shared decision-making
strategies, to guide treatment choices and measurable goals to
Transform therapeutic advances and
resource utilization data into informed health plan decisions
and formulary discussions for managed care professionals
||April W Armstrong, MD,
Associate Dean and Director of Clinical Research
Southern California Clinical and Translational Science
Director of Psoriasis Program, Department of Dermatology
University of Southern California Keck School of
Armstrong serves as a consultant for Abbvie,
Bristol-Myers Squibb, Dermavant, Eli Lilly, Janssen, Leo
Pharma Modernizing Medicine, Novartis, Ortho
Dermatologics, Pfizer, Regeneron, Sanofi Genzyme, and
Sun Pharma. She has received grants or research from
Abbvie, Bristol-Myers Squibb, Dermira, Eli Lilly,
Janssen, Kyowa Hakko Kirin, Leo Pharma, Novartis,
Regeneron Pharmaceuticals, Sanofi Genzyme, and UCB
Biopharma. Her presentation has been peer reviewed for
MD has no real or perceived financial relationships to
Jeremy Williams has no real or perceived financial
relationships to disclose.
Jacqueline Cole, RN, MS, CMCN has no real or perceived
financial relationships to disclose.
NAMCP and/or the presenter
has copyright or has received permissions for use of
materials provided in this activity.
Accreditation & Designation
This activity has been planned and implemented in accordance with
the accreditation requirements and policies of the Accreditation
Council for Continuing Medical Education (ACCME) through the joint
providership of the National Association of Managed Care Physicians
(NAMCP) and American Association of Managed Care Nurses (AAMCN). The
National Association of Managed Care Physicians is accredited by the
ACCME to provide continuing medical education for physicians.
NAMCP designates this enduring material for a maximum of 1 AMA
PRA Category 1 credit(s)TM. Each
physician should claim credit commensurate with the extent of their
participation in the activity.
The American Association of Managed Care Nurses is accredited as a
provider of nursing continuing professional development by the
American Nurses Credentialing Center's Commission on Accreditation.
Nurses who complete this activity and achieve a passing score will
receive 1 hour in nursing continuing professional development.
This activity has been approved by the American Board of Managed
Care Nursing for 1.0 contact hours toward CMCN recertification
This activity is supported by
an educational grant from
NAMCP and/or this website does not
provide medical advice, diagnosis or treatment. NAMCP does not
endorse or imply endorsement of the content on any linked website.
This website is to be used as an informational resource. With any
health related concern, consult with your physician or healthcare
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