Instructions for CME/NCPD: Complete the pre-test, listen to the
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If you do not pass the post test after two attempts, you will not be
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This activity is intended for healthcare professionals practicing in
managed care environments.
This activity is supported by
an educational grant from
The American Diabetes Association (ADA) estimates that more than
30.3 million people in the United States, or 9.4 percent of the
population, have diabetes, and that one in three Americans born in
2019 will develop diabetes sometime during their lifetime. About
90-95% of adults who have diabetes have type 2 diabetes mellitus
(DM). According to the Centers for Disease Control (CDC),
uncontrolled type 2 DM doubles a person’s risk for death, and on
average individuals with type 2 DM lose 10-15 years of life. The
management of type 2 DM remains a major challenge as many patients
continue to struggle with achieving therapeutic goals, including
control of A1C level, blood pressure, cholesterol, and weight.
Fortunately, recent advances in treatments in Type 2 Diabetes
management have given healthcare professionals the ability to shrink
this clinical practice gap. The economic cost of diabetes is
staggering. According to the National Diabetes Information
Clearinghouse and ADA, the total estimated cost of diabetes is about
$174 billion, including $116 billion in direct medical costs and $58
billion in reduced national productivity. Medical costs attributed
to diabetes included $27 billion for care to directly treat
diabetes, $58 billion to treat the portion of diabetes-related
chronic complications that are attributed to diabetes, and $31
billion in excess general medical costs. Moreover, it has been
estimated that people with diagnosed diabetes, on average, have
medical expenditures that are approximately 2.3 times higher than
what expenditures would be in the absence of diabetes. The price tag
associated with treatment of type 2 DM increases with disease
severity, as more and more dollars are spent managing the
significant comorbidities, such as cardiovascular disease,
associated with advanced type 2 DM.
Upon completion of this
activity, participants will be able to:
Assess the pathophysiologic
relationships between T2DM and cardiovascular disease (CVD),
heart failure (HF), and chronic kidney disease (CKD), including
implications for antihyperglycemic treatment
Examine the mechanism(s) supporting
the therapeutic potential of SGLT2 inhibitors to target
cardiorenal endpoints in patients with T2DM
Evaluate safety and efficacy results
from clinical trials and real-world studies of SGLT2 inhibitors
to optimize cardiorenal outcomes in patients with T2DM
Compare the designs and results of
large-scale cardiovascular and renal outcomes trials with SGLT2
inhibitors for T2DM
Collaborate with managed care
professionals and clinicians to manage patients with T2DM based
on cardiovascular and renal risks, recent guideline
recommendations, and other clinical parameters
Assess the managed care
considerations of SGLT2 inhibitors by exploring where these
agents fit into the evolving T2DM management paradigm for
optimizing cardiovascular and renal outcomes
||Richard E. Pratley, MD
Samuel E. Crockett Chair in Diabetes Research
Medical Director, AdventHealth Diabetes Institute
Adjunct Professor of Medicine, Johns Hopkins University
School of Medicine
serves as a consultant for Merck, Novo Nordisk, Pfizer,
Sanofi, Scohia Pharma, and Sun Pharmaceuticals. He
serves on the speaker's bureau for Novo Nordisk. He has
received grants/research funding from Hanmi
Pharmaceutical Company, Janssen, Metavention, Novo
Nordisk, Poxel SA, and Sanofi. His presentation has been
peer reviewed for any bias. His presentation has been
reviewed for any bias.
MD has no financial relationships with ineligible
companies to disclose.
Jeremy Williams has no financial relationships with
ineligible companies to disclose.
Jacqueline Cole, RN, MS, CMCN has no financial
relationships with ineligible companies to disclose.
NAMCP and/or the presenter
has copyright or has received permissions for use of
materials provided in this activity.
Accreditation & Designation
This activity has been planned and implemented in accordance with
the accreditation requirements and policies of the Accreditation
Council for Continuing Medical Education (ACCME) through the joint
providership of the National Association of Managed Care Physicians
(NAMCP) and American Association of Managed Care Nurses (AAMCN). The
National Association of Managed Care Physicians is accredited by the
ACCME to provide continuing medical education for physicians.
NAMCP designates this enduring material for a maximum of 1 AMA
PRA Category 1 credit(s)TM. Each
physician should claim credit commensurate with the extent of their
participation in the activity.
The American Association of Managed Care Nurses is accredited as a
provider of nursing continuing professional development by the
American Nurses Credentialing Center's Commission on Accreditation.
Nurses who complete this activity and achieve a passing score will
receive 1 hour in nursing continuing professional development.
This activity has been approved by the American Board of Managed
Care Nursing for 1.0 contact hours toward CMCN recertification
This activity is supported by an educational grant from
NAMCP and/or this website does not
provide medical advice, diagnosis or treatment. NAMCP does not
endorse or imply endorsement of the content on any linked website.
This website is to be used as an informational resource. With any
health related concern, consult with your physician or healthcare
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