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This activity is intended for healthcare professionals practicing in
managed care environments.
This activity is supported by
an educational grant from
Mitsubishi Tanabe Pharma America
Amyotrophic lateral sclerosis (ALS), more commonly known as Lou
Gehrig’s disease, is a progressive neurodegenerative disease that
affects nerve cells in the brain and the spinal cord. An estimated
20,000 people in the United States are living with ALS. It is a
progressive disease in which the motor neurons eventually die.
Mortality is usually the result of respiratory failure. Although
most patients with ALS die within 3 to 5 years after symptoms first
appear, about 20% of patients with ALS will live 5 years, 10% will
live 10 years, and about 5% will live 20 years or more. Currently,
there is no cure for ALS. Fortunately for patients with ALS, the
treatment paradigm has expanded in recent years, giving medical
directors and clinicians many more options in managing symptoms and
delaying progression in the ALS patient population. With new options
expanding the treatment armamentarium in ALS, a knowledge gap has
been created, making it imperative that managed care physician
medical directors, practicing physicians, pharmacists, payers,
nurses and other healthcare professionals who manage ALS patient
populations have a solid understanding of differing options to
optimize both costs and patient outcomes in their therapeutic
As there is no current cure for ALS, management focuses on treating
symptoms and providing supportive care, with the goal of improving
quality of life and prolonging survival in patients. This care is
best provided by multidisciplinary teams of healthcare
professionals; attending a multidisciplinary ALS clinic is
associated with longer survival, fewer hospitalizations, and
improved quality of life as they have access to the most recent
treatments and management tools. New agents have recently become
available that have shown the ability to slow functional decline in
ALS, giving providers and payers even more options to manage these
populations and improve quality of life. It is for this reason that
managed care physician medical directors, practicing physicians,
pharmacists, payers, nurses and other healthcare professionals are
brought up to date on all of the available and emerging therapy
options, the economic and quality of life burden that ALS presents,
and strategies for improving patient outcomes.
Upon completion of this
activity, participants will be able to:
Assess the clinical and economic
burden of amyotrophic lateral sclerosis (ALS) from population
and patient perspectives
Differentiate the mechanisms of
action and clinical data for currently approved treatments in
Examine the disease progression of
ALS and the benefit of early recognition
Investigate multidisciplinary care
approaches to treating patients with ALS and optimize the
management of symptoms associated with ALS with novel treatment
Discuss utilization management
considerations in ALS, including best practices and new and
Assess the managed care
considerations of newer therapies that slow disease progression,
by exploring where these agents fit in the evolving ALS
||Hiroshi Mitsumoto, MD,
Wesley J Howe Professor of Neurology
Eleanor and Lou Gehrig ALS Center
Department of Neurology
Columbia University Medical Center
Mitsumoto has received research grants from ALS
Association, SPF, MDA Wings, NIH, MNDA, Tsumura & Co,
and Mitsubishi-Tanabe Pharma. He has served on an
advisory board for Amylyx.
MD has no financial relationships with ineligible
companies to disclose.
Jeremy Williams has no financial relationships with
ineligible companies to disclose.
Jacqueline Cole, RN, MS, CMCN has no financial
relationships with ineligible companies to disclose.
NAMCP and/or the presenter
has copyright or has received permissions for use of
materials provided in this activity.
Accreditation & Designation
This activity has been planned and implemented in accordance with
the accreditation requirements and policies of the Accreditation
Council for Continuing Medical Education (ACCME) through the joint
providership of the National Association of Managed Care Physicians
(NAMCP) and American Association of Managed Care Nurses (AAMCN). The
National Association of Managed Care Physicians is accredited by the
ACCME to provide continuing medical education for physicians.
NAMCP designates this enduring material for a maximum of 1 AMA
PRA Category 1 credit(s)TM. Each
physician should claim credit commensurate with the extent of their
participation in the activity.
The American Association of Managed Care Nurses is accredited as a
provider of nursing continuing professional development by the
American Nurses Credentialing Center's Commission on Accreditation.
Nurses who complete this activity and achieve a passing score will
receive 1 hour in nursing continuing professional development.
This activity has been approved by the American Board of Managed
Care Nursing for 1.0 contact hours toward CMCN recertification
This activity is supported by an educational grant from
Mitsubishi Tanabe Pharma America
NAMCP and/or this website does not
provide medical advice, diagnosis or treatment. NAMCP does not
endorse or imply endorsement of the content on any linked website.
This website is to be used as an informational resource. With any
health related concern, consult with your physician or healthcare
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