Recent Developments in the Treatment and
Management of Psoriatic Arthritis
A continuing medical education activity sponsored by NAMCP and AAMCN.
This activity is an archive from the
live session from the 2020 Spring Managed Care Forum. If you
participated in the live session, you are not eligible for
continuing education credits from this archive
This activity is valid from June 1, 2020 to
June 1, 2021
Instructions for CME/NCPD: Complete the pre-test, listen to the
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Audience: This activity is intended for
healthcare professionals practicing in managed care environments.
This presentation is supported by an
educational grant from
Novartis Pharmaceuticals Corporation
Psoriatic arthritis is a progressive, inflammatory disease that is
associated with a number of dermatologic and musculoskeletal
manifestations. Patients can experience extreme pain and joint
damage that may affect their quality of life, physical function, and
ability to work. Symptoms include fatigue, joint inflammation, and
potentially progressive joint damage. Diagnosing psoriatic arthritis
can be very complex with the most critical factor being the absence
of validated criteria for identifying and classifying cases that
will help diagnose the disease. The standard diagnostic measures are
based on history, a physical exam and x-ray features, so
establishing the presence of characteristic signs and symptoms
associated in both the skin and joints, and by ruling out more
common inflammatory arthritis, can be very helpful. The diagnosis of
psoriatic arthritis can sometimes be delayed or missed by primary
care providers and other healthcare professionals. The past few
years have seen a number of treatments introduced for psoriatic
arthritis. Along with symptomatic treatments, such as nonsteroidal
anti-inflammatory drugs (NSAIDs), corticosteroids, and local
corticosteroid injections into joints, there are also the oral small
molecules (OSMs) for treatment. The Tumor Necrosis Factor (TNF)
inhibitors have been available for nearly 20 years and continue to
be a viable option for patients. More recently key cytokines in the
psoriatic disease pathophysiology have been introduced and they
include Janus kinases and signal transducers and activators of
transcription (JAK-STATs) as well as are the interleukin (IL)-12,
IL-17, IL-22 and IL-23 pathway inhibitors. These newer biologic
treatments target some of these key cytokines to treat psoriatic
Upon completion of this
activity, participants will be able to:
Identify treatment strategies
explaining psoriatic arthritis (PsA) pathophysiology and
mechanisms of action of targeted therapies for PsA
Assess different strategies to
evaluate PsA severity that incorporate both joint and skin
manifestation in order to guide appropriate management plans
Explore clinical evidence of
effectiveness and safety of targeted biologic and small-molecule
therapies to guide treatment decisions for patients with PsA
Identify individualized management
plans for newly diagnosed patients with PsA, including the
long-term treatment impact of current biologics
Evaluate multidisciplinary care team
strategies to overcome different challenges in PsA management
||Allan Gibofsky, MD, JD
Professor of Medicine, Healthcare Policy and Research
Weill Medical College of Cornell University
Hospital for Special Surgery
Gibofsky serves on an advisory board and is a consultant
for AbbVie, Gilead, Lilly, Novartis, and Pfizer. He
serves on the speaker's bureau for AbbVie, Lilly,
Novartis, and Pfizer. He owns and self-manages stock in
AbbVie, BMS, Lilly, and Pfizer. His presentation has
been peer reviewed for any bias.
MD has no relevant financial relationships to disclose.
Jeremy Williams has no relevant financial relationships
Will Williams has no relevant financial relationships to
Jacqueline Cole, RN, MS, CMCN has no relevant financial
relationships to disclose.
NAMCP and/or the presenter
has copyright or has received permissions for use of
materials provided in this activity.
Accreditation & Designation
This activity has been planned and implemented in accordance with
the accreditation requirements and policies of the Accreditation
Council for Continuing Medical Education (ACCME) through the joint
providership of the National Association of Managed Care Physicians
(NAMCP) and American Association of Managed Care Nurses (AAMCN). The
National Association of Managed Care Physicians is accredited by the
ACCME to provide continuing medical education for physicians.
NAMCP designates this enduring material for a maximum of 1 AMA
PRA Category 1 credit(s)TM. Each
physician should claim credit commensurate with the extent of their
participation in the activity.
The American Association of Managed Care Nurses is accredited as a
provider of nursing continuing professional development by the
American Nurses Credentialing Center's Commission on Accreditation.
Nurses who complete this activity and achieve a passing score will
receive 1 hour in nursing continuing professional development.
This activity has been approved by the American Board of Managed
Care Nursing for 1.0 contact hours toward CMCN recertification
This presentation is supported by
an educational grant from
Novartis Pharmaceuticals Corporation
NAMCP and/or this website does not
provide medical advice, diagnosis or treatment. NAMCP does not
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