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This activity is intended for healthcare professionals practicing in
managed care environments.
This activity is supported by
educational grants from
AbbVie and Novartis Pharmaceuticals Corporation
Psoriatic arthritis is a debilitating disease that may affect up to
1 million adults in the United States, affecting men and women
equally. Psoriatic arthritis is a progressive, inflammatory disease
that is associated with a number of dermatologic and musculoskeletal
manifestations. Patients can experience extreme pain and joint
damage that may affect their quality of life, physical function, and
ability to work. Symptoms include fatigue, joint inflammation, and
potentially progressive joint damage.Diagnosing psoriatic arthritis
can be very complex and the standard diagnostic measures are based
on history, a physical exam and x-ray features, so establishing the
presence of characteristic signs and symptoms associated in both the
skin and joints, and by ruling out more common inflammatory
arthritis, can be very helpful. The most commonly accepted
diagnostic criterion is the CAPSER classification. The diagnosis of
psoriatic arthritis can sometimes be delayed or missed by primary
care providers and other healthcare professionals. With recent
updates to the guidelines, there have been updates and advances in
digital imaging tools and screening options that have improved the
chances of catching psoriatic arthritis early, which allows for
better treatment goals to be achieved.
The past few years have seen a number of treatments introduced for
psoriatic arthritis. Along with symptomatic treatments, such as
nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and
local corticosteroid injections into joints, there are also the oral
small molecules (OSMs) for treatment. The Tumor Necrosis Factor (TNF)
inhibitors have been available for nearly 20 years and continue to
be a viable option for patients. More recently key cytokines in the
psoriatic disease pathophysiology have been introduced and they
include Janus kinases and signal transducers and activators of
transcription (JAK-STATs) as well as are the interleukin (IL)-12,
IL-17, IL-22 and IL-23 pathway inhibitors. These newer biologic
treatments target some of these key cytokines to treat psoriatic
disease. Clinicians need to be able to incorporate these new
approaches into treatment paradigms, considering both safety and
efficacy, by being educated with appropriate management strategies
that will guide treatment decisions for patients with psoriatic
Upon completion of this
activity, participants will be able to:
Analyze clinical tools for assessing
joint symptoms and diagnosing psoriatic arthritis (PsA)
Discuss the current guidelines and
evidence to make appropriate decisions for patients who require
systemic targeted therapies in PsA
Explore new and emerging targeted
therapies for PsA based on mechanisms of action, efficacy and
safety data, and comparative effectiveness
Assess short and long-term
strategies that account for risk management in patients with PsA
approaches for effective PsA treatment and management to address
common comorbidities, adherence, and adverse events
||Leonard H. Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine
Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Calabrese serves as a consultant for AbbVie, Bristol
Myers Squibb, Genentech, Janssen, Lilly, Novartis and
UCB. His presentation has been peer reviewed for any
MD has no financial relationships with ineligible
companies to disclose.
Jeremy Williams has no financial relationships with
ineligible companies to disclose.
Jacqueline Cole, RN, MS, CMCN has no financial
relationships with ineligible companies to disclose.
NAMCP and/or the presenter
has copyright or has received permissions for use of
materials provided in this activity.
Accreditation & Designation
This activity has been planned and implemented in accordance with
the accreditation requirements and policies of the Accreditation
Council for Continuing Medical Education (ACCME) through the joint
providership of the National Association of Managed Care Physicians
(NAMCP) and American Association of Managed Care Nurses (AAMCN). The
National Association of Managed Care Physicians is accredited by the
ACCME to provide continuing medical education for physicians.
NAMCP designates this enduring material for a maximum of 1 AMA
PRA Category 1 credit(s)TM. Each
physician should claim credit commensurate with the extent of their
participation in the activity.
The American Association of Managed Care Nurses is accredited as a
provider of nursing continuing professional development by the
American Nurses Credentialing Center's Commission on Accreditation.
Nurses who complete this activity and achieve a passing score will
receive 1 hour in nursing continuing professional development.
This activity has been approved by the American Board of Managed
Care Nursing for 1.0 contact hours toward CMCN recertification
This activity is supported by educational grants from
AbbVie and Novartis Pharmaceuticals Corporation
NAMCP and/or this website does not
provide medical advice, diagnosis or treatment. NAMCP does not
endorse or imply endorsement of the content on any linked website.
This website is to be used as an informational resource. With any
health related concern, consult with your physician or healthcare
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