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Audience:
This activity is intended for healthcare professionals practicing in
managed care environments.
This activity is supported by educational grants from
AstraZeneca, GlaxoSmithKline, and Merck Sharp & Dohme LLC
Description:
There were an estimated 19,880 new cases of ovarian cancer last year
in the United States, and an estimated 12,8110 deaths due to ovarian
cancer in the US, according to the American Cancer Society. Ovarian
cancer is usually found late, stage 3 or higher, where it has
already spread or metastasized to other parts of the abdomen, or
worse. This is due in large part to a lack of symptoms during the
earlier stages. The five year survival rate is only 45%. Fortunately
for patients with ovarian cancer, the treatment paradigm has
exploded in the past three years, giving medical directors and
clinicians more options in managing patients with ovarian cancer.
Leading the way in new options for ovarian cancer are poly
(ADP-ribose) polymerase (PARP) inhibitors, which have shown improved
efficacy for patients with ovarian cancer. Additionally, new
indications for these targeted agents offer expanded options in the
maintenance setting in the first-line setting. It is important for
medical directors, oncologists, and nurses who manage ovarian cancer
patient populations to have a solid understanding of the mechanistic
rationale for the use of these medications in order to optimize
their therapeutic application.
Upon completion of this
activity, participants will be able to:
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Assess the clinical and economic
burden of ovarian cancer, including factors that contribute to
poor prognosis and increased costs
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Explore the nuances that
differentiate the available PARP inhibitors that aid in guiding
treatment selection
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Examine guideline recommendations
and recent clinical data on the use PARP inhibitors in various
stages of treatment in ovarian cancer
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Identify patients with advanced
ovarian cancer for whom a PARP inhibitor is an appropriate
choice for the next step in the management of their cancer
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Evaluate practical strategies to
recognize and manage adverse events related to PARP inhibitor
use ovarian cancer, particularly in the long-term maintenance
setting
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Determine the cost of care and
utilization management strategies to optimize the use of PARP
inhibitors in the treatment of ovarian cancer
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Faculty: |
Kathleen N. Moore, MD,
MS
Associate Director, Clinical Research
Virginia Kerley Cade Chair in Developmental Therapeutics
Director, TSET Phase I Drug Unit
Co-Director, Cancer Therapeutics Program
Stephenson Cancer Center at the University of Oklahoma
HSC |
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Disclosure:
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(Relevant Financial Relationships with Ineligible
Companies in the Last 24 Months):
Dr. Moore has served as a consultant for Aadi,
AstraZeneca, Alkemeres, Aravive, Blueprint, Clovis,
Caris, Eisai, GSK/Tesaro, Genentech/Roche, Immunogen,
Lilly, Mereo, Mersana, Myriad, Merck, Novartis, OncXerna,
OncoNova, VBL Therapeutics, and Pannavance. Her
presentation has been reviewed for any bias. |
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Planning Committee: |
Bill
Williams, MD has no relevant financial relationships
with an ineligible company in the last 24 months to
disclose.
Jeremy Williams has no relevant financial relationships
with an ineligible company in the last 24 months to
disclose.
Jacqueline Cole, RN, MS, CMCN has no relevant financial
relationships with an ineligible company in the last 24
months to disclose.
NAMCP and/or the presenter
has copyright or has received permissions for use of
materials provided in this activity. |
Accreditation & Designation
This activity has been planned and implemented in accordance with
the accreditation requirements and policies of the Accreditation
Council for Continuing Medical Education (ACCME) through the joint
providership of the National Association of Managed Care Physicians
(NAMCP) and American Association of Managed Care Nurses (AAMCN). The
National Association of Managed Care Physicians is accredited by the
ACCME to provide continuing medical education for physicians.
NAMCP designates this enduring material for a maximum of 1 AMA
PRA Category 1 credit(s)TM. Each
physician should claim credit commensurate with the extent of their
participation in the activity.
The American Association of Managed Care Nurses is accredited as a
provider of nursing continuing professional development by the
American Nurses Credentialing Center's Commission on Accreditation.
Nurses who complete this activity and achieve a passing score will
receive 1 hour in nursing continuing professional development.
This activity has been approved by the American Board of Managed
Care Nursing for 1.0 contact hours toward CMCN recertification
requirements.
This activity is supported by educational grants from
AstraZeneca, GlaxoSmithKline, and Merck Sharp & Dohme LLC
NAMCP and/or this website does not
provide medical advice, diagnosis or treatment. NAMCP does not
endorse or imply endorsement of the content on any linked website.
This website is to be used as an informational resource. With any
health related concern, consult with your physician or healthcare
professional.
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