Navigating Treatment Strategies in the Management of Metastatic Bladder Cancer: Expert Perspectives in Immunotherapy

A continuing medical education activity sponsored by NAMCP and AAMCN.

This activity is an archive from the live session from the 2019 Fall Managed Care Forum. If you participated in the live session, you are not eligible for continuing education credits from this archive.

This activity is valid from January 1, 2020 to January 1, 2021

Instructions for CME/CNE: Complete the pre-test, listen to the audio and view the slides, complete the post test, complete the evaluation form and hit submit. You will be asked to enter your name and email address on the pre-test, evaluation and post-test. If you close your internet browser without completing the post test, you will have ONE more opportunity to complete. A score of 70% must be achieved on the post test to receive continuing education credits. If you do not pass the post test after two attempts, you will not be eligible to try again. Once you complete the evaluation form and score 70% or higher on your post test, you will automatically be given your certificate.

To print or save your certificate, you will need to click on the “download” button and either print or save.

 

Audience: This activity is intended for healthcare professionals practicing in managed care environments.

This presentation is supported by an educational grant from
Merck Sharp & Dohme Corp.

Description:
Bladder cancer, also known as urothelial carcinoma, is the ninth leading cause of cancer death in the United States. Before the advent of new treatments in recent years, the basic management of this illness has remained unchanged for decades. Long-term survival for people diagnosed with advanced bladder cancer is poor, with approximately 5% of patients surviving for 5 years or more. New and emerging treatments, in particular, immune checkpoint inhibitors have changed the treatment paradigm. Checkpoint inhibitors have shown activity in patients with metastatic bladder cancer in both the first and second-line settings. Some of the new immunotherapeutic options target a protein known as PD-L1 that is expressed at high levels on some cancer cells, while others target PD-1, the receptor protein for PD-L1, on immune cells. Normally, binding of PD-L1 to PD-1 tamps down immune activity. By preventing the interaction between PD-L1 and PD-1, all of these new options can allow the immune system to be more active against tumor cells.

Upon completion of this activity, participants will be able to:

  • Analyze the role of immune checkpoint inhibitors in the first-line treatment of metastatic bladder cancer

  • Explore efficacy and safety profiles of current and emerging immune checkpoint inhibitors for the treatment of metastatic bladder cancer

  • Assess the latest clinical evidence regarding predictors of response to immunotherapy in metastatic bladder cancer

  • Identify patients who would potentially benefit from immunotherapies in metastatic bladder cancer

  • Define strategies for anticipating, recognizing, and managing immune-related adverse events of immunotherapy in patients with metastatic bladder cancer
     

Faculty: Matthew Galsky, MD
Professor of Medicine
Genitourinary Medical Oncology
Icahn School of Medicine at Mount Sinai
Director, Novel Therapeutics Unit
Tisch Cancer Institute

Disclosure:

Dr. Galsky serves on an advisory board for AstraZeneca, BMS, Genentech, Merck, and Pfizer. He has received grant/research support from AstraZeneca, BMS, Genentech, and Merck. His presentation has been peer reviewed for any bias.
 
  Planning Committee:
Bill Williams, MD has no relevant financial relationships to disclose.
Jeremy Williams has no relevant financial relationships to disclose.
Will Williams has no relevant financial relationships to disclose.
Jacqueline Cole, RN, MS, CMCN has no relevant financial relationships to disclose.

NAMCP and/or the presenter has copyright or has received permissions for use of materials provided in this activity.

Accreditation & Designation
The National Association of Managed Care Physicians (NAMCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

NAMCP designates this enduring material for a maximum of 1 AMA PRA Category 1 creditsTM.

The American Association of Managed Care Nurses (AAMCN) is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

Nurses who complete this activity and achieve a passing score will receive 1 hour in continuing
nursing credit.

This activity has been approved by the American Board of Managed Care Nursing for 1.0 contact hour toward CMCN recertification requirements.

This presentation is supported by an educational grant from
Merck Sharp & Dohme Corp.

NAMCP and/or this website does not provide medical advice, diagnosis or treatment. NAMCP does not endorse or imply endorsement of the content on any linked website. This website is to be used as an informational resource. With any health related concern, consult with your physician or healthcare professional.

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